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1

Phosphinic Tripeptides as Dual Angiotensin-Converting Enzyme C-Domain and Endothelin-Converting Enzyme-1 Inhibitors

Jullien, Nicolas, Makritis, Anastasios, Georgiadis, Dimitris, Beau, Fabrice, Yiotakis, Athanasios, Dive, Vincent

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2010

2

Cross-Linking Yield Variation of a Potent Matrix Metalloproteinase Photoaffinity Probe and Consequences for Functional Proteomics

Arnaud David, David Steer, Sarah Bregant, Laurent Devel, Anastasios Makaritis, Fabrice Beau, Athanasios Yiotakis, Vincent Dive

Journal:

Angewandte Chemie

Année:

2007

Langue:

english

Fichier:

PDF, 160 KB

english, 2007

3

Cross-Linking Yield Variation of a Potent Matrix Metalloproteinase Photoaffinity Probe and Consequences for Functional Proteomics

Arnaud David, David Steer, Sarah Bregant, Laurent Devel, Anastasios Makaritis, Fabrice Beau, Athanasios Yiotakis, Vincent Dive

Journal:

Angewandte Chemie International Edition

Année:

2007

Langue:

english

Fichier:

PDF, 160 KB

english, 2007

4

Proton and tritium nmr relaxation studies of peptide inhibitor binding to bacterial collagenase: Conformation and dynamics

Vincent Dive, Adolfo Lai, Gianni Valensin, Giuseppe Saba, Athanasios Yiotakis, Flavio Toma

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1004 KB

english, 1991

5

Diastereoselective Solution and Multipin-Based Combinatorial Array Synthesis of a Novel Class of Potent Phosphinic Metalloprotease Inhibitors

Anastasios Makaritis, Dimitris Georgiadis, Vincent Dive, Athanasios Yiotakis

Journal:

Chemistry - A European Journal

Année:

2003

Langue:

english

Fichier:

PDF, 402 KB

english, 2003

6

ChemInform Abstract: A Highly Efficient Method for the Preparation of Phosphinic Pseudodipeptidic Blocks Suitably Protected for Solid-Phase Peptide Synthesis.

Dimitris Georgiadis, Magdalini Matziari, Athanasios Yiotakis

Journal:

Année:

2001

Fichier:

PDF, 29 KB

2001

7

ChemInform Abstract: A Modular Rearrangement Approach Toward Medicinally Relevant Phosphinic Structures.

Vassilis Rogakos, Dimitris Georgiadis, Vincent Dive, Athanasios Yiotakis

Journal:

Année:

2010

Fichier:

PDF, 65 KB

2010

8

Matrix metalloproteinase inhibition protects rat livers from prolonged cold ischemia–warm reperfusion injury

Virginie Defamie, Marina Laurens, Damiano Patrono, Laurent Devel, Antoine Brault, Marie-Christine Saint-Paul, Athanasios Yiotakis, Pascal Barbry, Jean Gugenheim, Dominique Crenesse, Vincent Dive, Pier

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2008

9

Dosing and scheduling influence the antitumor efficacy of a phosphinic peptide inhibitor of matrix metalloproteinases

Vincent Dive, Kumari L. Andarawewa, Anne Boulay, Magdalini Matziari, Fabrice Beau, Eric Guerin, Bernard Rousseau, Athanasios Yiotakis, Marie-Christine Rio

Journal:

International Journal of Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 290 KB

english, 2005

10

Matrix metalloproteinase 11 (MMP-11; stromelysin-3) and synthetic inhibitors

Magdalini Matziari, Vincent Dive, Athanasios Yiotakis

Journal:

Medicinal Research Reviews

Année:

2007

Langue:

english

Fichier:

PDF, 457 KB

english, 2007

11

Vasoactive intestinal peptide (VIP) from chicken: Synthesis and properties of the C-terminal hendecapeptide

Miklos Bodanszky, Cynthia Yang Lin, Athanasios E. Yiotakis, Viktor Mutt, Sami I. Said

Journal:

Bioorganic Chemistry

Année:

1976

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1976

12

A synthetic method for diversification of the P1′ substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1′ binding pockets of leucine aminopeptidases

Stamatia Vassiliou, Metaxia Xeilari, Athanasios Yiotakis, Jolanta Grembecka, Małgorzata Pawełczak, Paweł Kafarski, Artur Mucha

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 369 KB

english, 2007

13

Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge

Dimitris Georgiadis, Athanasios Yiotakis

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 349 KB

english, 2008

14

A simple synthesis of the metabotropic receptor ligand (2S)-α-(hydroxymethyl)-glutamic acid and its Fmoc protected derivatives

Athanasios Yiotakis, Plato A. Magriotis, Stamatia Vassiliou

Journal:

Tetrahedron: Asymmetry

Année:

2007

Langue:

english

Fichier:

PDF, 155 KB

english, 2007

15

Efficient enantioselective synthesis of orthogonally protected (R)-α-alkylserines compatible with the solid phase peptide synthesis

Stamatia Vassiliou, Athanasios Yiotakis, Plato A. Magriotis

Journal:

Tetrahedron Letters

Année:

2006

Langue:

english

Fichier:

PDF, 113 KB

english, 2006

16

Corrigendum to “A Convenient Method to Synthesize Phosphinic Peptides Containing an Aspartyl or Glutamyl Aminophosphinic Acid. Use of the Phenyl Group as the Carboxyl Synthon”: [Tetrahedron 55 (1999) 14635]

Dimitris Georgiadis, Magdalini Matziari, Stamatia Vassiliou, Vincent Dive, Athanasios Yiotakis

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 37 KB

english, 2000

17

A highly efficient method for the preparation of phosphinic pseudodipeptidic blocks suitably protected for solid-phase peptide synthesis

Dimitris Georgiadis, Magdalini Matziari, Athanasios Yiotakis

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 145 KB

english, 2001

18

A convenient method to synthesize phosphinic peptides containing an aspartyl or glutamyl aminophosphinic acid. Use of the phenyl group as the carboxyl synthon

Dimitris Georgiadis, Magdalini Matziari, Stamatia Vassiliou, Vincent Dive, Athanasios Yiotakis

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1999

19

Combining Combinatorial Chemistry and Affinity Chromatography: Highly Selective Inhibitors of Human Betaine: Homocysteine S-Methyltransferase

Michaela Collinsová, Carmen Castro, Timothy A Garrow, Athanasios Yiotakis, Vincent Dive, Jiřı́ Jiráček

Journal:

Chemistry & Biology

Année:

2003

Langue:

english

Fichier:

PDF, 214 KB

english, 2003

20

Tissue inhibitor of metalloproteinases-1 (TIMP-1) modulates neuronal death, axonal plasticity, and learning and memory

Jérôme Jourquin, Evelyne Tremblay, Anne Bernard, Gérard Charton, Franck A. Chaillan, Evelyne Marchetti, François S. Roman, Paul D. Soloway, Vincent Dive, Athanasios Yiotakis, Michel Khrestchatisky, Sa

Journal:

European Journal of Neuroscience

Année:

2005

Langue:

english

Fichier:

PDF, 658 KB

english, 2005

21

Combined use of selective inhibitors and fluorogenic substrates to study the specificity of somatic wild-type angiotensin-converting enzyme

Nicolas D. Jullien, Philippe Cuniasse, Dimitris Georgiadis, Athanasios Yiotakis, Vincent Dive

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 383 KB

english, 2006

22

Structure of astacin with a transition-state analogue inhibitor

Grams, Frank, Dive, Vincent, Yiotakis, Athanasios, Yiallouros, Irene, Vassiliou, Stamatia, Zwilling, Robert, Bode, Wolfram, Stöcker, Walter

Journal:

Natural Structural Biology

Année:

1996

Fichier:

PDF, 826 KB

1996

23

Computer-Aided Optimization of Phosphinic Inhibitors of Bacterial Ureases

Vassiliou, Stamatia, Kosikowska, Paulina, Grabowiecka, Agnieszka, Yiotakis, Athanasios, Kafarski, Paweł, Berlicki, Łukasz

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 2.50 MB

english, 2010

24

Synthesis of the Phosphinic Analogue of Thyrotropin Releasing Hormone

Matziari, Magdalini, Bauer, Karl, Dive, Vincent, Yiotakis, Athanasios

Journal:

Journal of Organic Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 256 KB

english, 2008

25

Development of Potent and Selective Phosphinic Peptide Inhibitors of Angiotensin-Converting Enzyme 2

Mores, Andreas, Matziari, Magdalini, Beau, Fabrice, Cuniasse, Philippe, Yiotakis, Athanasios, Dive, Vincent

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 347 KB

english, 2008

26

Allomalformin

MIKLOS BODANSZKY, MARIA A. BEDNAREK, ATHANASIOS E. YIOTAKIS, ROY W. CURTIS

Journal:

Chemical Biology & Drug Design

Année:

1982

Langue:

english

Fichier:

PDF, 730 KB

english, 1982

27

Peptide inhibitors of E. collagenolyticum bacterial collagenase -effect of N-methylation : Consequences on biological activity and conformational properties

VINCENT DIVE, ATHANASIOS YIOTAKIS, CHRISTIAN ROUMESTAND, BERNARD GILQUIN, JEAN LABADIE, FLAVIO TOMA

Journal:

Chemical Biology & Drug Design

Année:

1992

Langue:

english

Fichier:

PDF, 837 KB

english, 1992

28

New thiol inhibitor of Achromobacter iophagus collagenase : Specificity of the enzyme's S3′ subsite

Athanasios YIOTAKIS, Vincent DIVE

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 424 KB

english, 1986

29

New thiol inhibitor of Achromobacter iophagus collagenase : Specificity of the enzyme's S3′ subsite

Athanasios YIOTAKIS, Vincent DIVE

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 653 KB

english, 1986

30

New thiol inhibitors of Clostridium histolyticum collagenase : Importance of the P3′ position

Athanasios YIOTAKIS, Athina HATGIYANNACOU, Vincent DIVE, Flavio TOMA

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 388 KB

english, 1988

31

New thiol inhibitors of Clostridium histolyticum collagenase : Importance of the P3′ position

Athanasios YIOTAKIS, Athina HATGIYANNACOU, Vincent DIVE, Flavio TOMA

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 734 KB

english, 1988

32

Inhibition of Clostridium histolyticum collagenases by phosphonamide peptide inhibitors

Vincent DIVE, Athanasios YIOTAKIS, Anna NICOLAOU, Flavio TOMA

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 635 KB

english, 1990

33

Inhibition of Clostridium histolyticum collagenases by phosphonamide peptide inhibitors

Vincent DIVE, Athanasios YIOTAKIS, Anna NICOLAOU, Flavio TOMA

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1001 KB

english, 1990

34

Phosphorus-containing peptides as mixed inhibitors of endopeptidase 3.4.24.15 and 3.4.24.16: effect on neurotensin degradation in vitro and in vivo

Bruno Vincent, Vincent Dive, Athanasios Yiotakis, Claire Smadja, Raphaël Maldonado, Jean-Pierre Vincent, * Frederic Checler

Journal:

British Journal of Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.74 MB

english, 1995

35

Evaluation of P1'-Diversified Phosphinic Peptides Leads to the Development of Highly Selective Inhibitors of MMP-11

Matziari, Magdalini, Beau, Fabrice, Cuniasse, Philippe, Dive, Vincent, Yiotakis, Athanasios

Journal:

Journal of Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 502 KB

english, 2004

36

Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state

Anne-Laure Gall, Marc Ruff, Rama Kannan, Philippe Cuniasse, Athanasios Yiotakis, Vincent Dive, Marie-Christine Rio, Paul Basset, Dino Moras

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 602 KB

english, 2001

37

Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity

Anna Tochowicz, Klaus Maskos, Robert Huber, Ruth Oltenfreiter, Vincent Dive, Athanasios Yiotakis, Matteo Zanda, Wolfram Bode, Peter Goettig

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2007

38

Corrigendum to “Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity” [Journal of Molecular Biology, 371 (2007), 989–1006]

Anna Tochowicz, Klaus Maskos, Robert Huber, Ruth Oltenfreiter, Vincent Dive, Athanasios Yiotakis, Matteo Zanda, Tayebeh Pourmotabbed, Wolfram Bode, Peter Goettig

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 76 KB

english, 2009

39

Synthetic active site-directed inhibitors of metzincins: Achievement and perspectives

Athanasios Yiotakis, Vincent Dive

Journal:

Molecular Aspects of Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 443 KB

english, 2008

40

Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release

Raymundo Cruz, Miguel Angel Vargas, Rosa Maria Uribe, Isel Pascual, Ivan Lazcano, Athanasios Yiotakis, Magdalini Matziari, Patricia Joseph-Bravo, Jean-Louis Charli

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2008

41

Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases

Vassiliou, Stamatia, Grabowiecka, Agnieszka, Kosikowska, Paulina, Yiotakis, Athanasios, Kafarski, Paweł, Berlicki, Łukasz

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 489 KB

english, 2008

42

Side reactions in peptide synthesis. 4. Extensive O-acylation by active esters in histidine containing peptides

Bodanszky, Miklos, Fink, Mary L., Klausner, Yakir S., Natarajan, Sesha, Tatemoto, Kazuhiko, Yiotakis, Athanasios E., Bodanszky, Agnes

Journal:

Journal of Organic Chemistry

Année:

1977

Langue:

english

Fichier:

PDF, 472 KB

english, 1977

43

Active Methylene Phosphinic Peptides: A New Diversification Approach

Matziari, Magdalini, Nasopoulou, Magdalini, Yiotakis, Athanasios

Journal:

Organic Letters

Année:

2006

Langue:

english

Fichier:

PDF, 85 KB

english, 2006

44

N ? -linked arginine peptides

Photaki, Iphigenia, Yiotakis, Athanasios

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 787 KB

english, 1976

45

RXP 407, a Phosphinic Peptide, Is a Potent Inhibitor of Angiotensin I Converting Enzyme Able to Differentiate between Its Two Active Sites

Vincent Dive, Joël Cotton, Athanasios Yiotakis, Annie Michaud, Stamatia Vassiliou, Jiri Jiracek, Gilles Vazeux, Marie-Thérèse Chauvet, Philippe Cuniasse and Pierre Corvol

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1999

46

Rapid Access to the Tricyclic Spirotetronic Core of Abyssomicins

Zografos, Alexandros L., Yiotakis, Athanasios, Georgiadis, Dimitris

Journal:

Organic Letters

Année:

2005

Langue:

english

Fichier:

PDF, 98 KB

english, 2005

47

Shortcut to Fmoc-Protected Phosphinic Pseudodipeptidic Blocks

Matziari, Magdalini, Yiotakis, Athanasios

Journal:

Organic Letters

Année:

2005

Langue:

english

Fichier:

PDF, 124 KB

english, 2005

48

Protection of the Hydroxyphosphinyl Function of Phosphinic Dipeptides by Adamantyl. Application to the Solid-Phase Synthesis of Phosphinic Peptides

Yiotakis, Athanasios, Vassiliou, Stamatia, Jiráček, Jiří, Dive, Vincent

Journal:

Journal of Organic Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 182 KB

english, 1996

49

Synthesis and pharmacological properties of the N-terminal decapeptide of the vasoactive intestinal peptide (VIP)

Bodanszky, Miklos, Henes, Jill B., Yiotakis, Athanasios E., Said, Sami I.

Journal:

Journal of Medicinal Chemistry

Année:

1977

Langue:

english

Fichier:

PDF, 580 KB

english, 1977

50

Synthesis and Comparative Study on the Reactivity of Peptidyl-Type Phosphinic Esters: Intramolecular Effects in the Alkaline and Acidic Cleavage of Methyl β-Carboxyphosphinates

Georgiadis, Dimitris, Dive, Vincent, Yiotakis, Athanasios

Journal:

Journal of Organic Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 98 KB

english, 2001